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2018

・ N. Gotoh, K. Nagao, H. Ishida, K. Nakamitsu, K. Yoshinaga, T. Nagai, F. Beppu, A. Yoshinaga-Kiriake., H. Watanabe, and T. Yanagita, Metabolism of natural highly unsaturated fatty acid, tetracosahexaenoic acid (24:6n-3), in C57BL/KsJ-db/db mice. J. Oleo Sci. (2018) accepted

・ K. Yoshinaga, J. Obi, A. Tago, Y. Kato, T. Nagai, A. Yoshida, and N. Gotoh, Analysis of hydroxy triacylglycerol as a lactone precursor in milk fat using liquid chromatography electrospray ionization tandem mass spectrometry. Food Chem. (2018). accepted

・ J. Obi, K. Yoshinaga, A. Tago, T. Nagai, A. Yoshida, F. Beppu, and N. Gotoh, Simple quantification of lactones in milk fat by solvent extraction using gas chromatography?mass spectrometry. J. Oleo Sci. 67, 941-948 (2018). [Paper (pdf)]

・ S. Senarath, K. Yoshinaga, T. Nagai, A. Yoshida, F. Beppu, and N. Gotoh, Differential effect of cis-eicosenoic acid positional isomers on adipogenesis and lipogenesis in 3T3-L1 cells.  Eur. J. Lipid Sci. Technol. 1700512 (2018). [Abstract]

・ N. Gotoh, S. Kagiono, K. Yoshinaga, H. Mizobe, T. Nagai, A. Yoshida, F. Beppu, and K. Nagao, Study on the trans fatty acid formation in oil by heating using model compounds. J. Oleo Sci. 67, 273-281 (2018). [Paper (pdf)].

・ F. Beppu, H. Kondo, S. Kasatani, Y. Aoki, and N. Gotoh, Quantitative analysis of marine-derived tocopherol accumulation in tissues of mice fed salmon roe oil by high-performance liquid chromatography fluorescence method. J. Oleo Sci. 67, 283-288 (2018). [Paper (pdf)].

2017

・ A. H. Yatmaz, T. Kinoshita, A. Miyazato, M. Takagi, Y. Tsujino, F. Beppu, and N. Gotoh, Quantification of Fraglide-1, a new functional ingredient, in vinegars. J. Oleo Sci. 66, 1381-1386 (2017). [Paper (pdf)].

・ T. Nagai, K Ishikawa, K. Yoshinaga, A. Yoshida, F. Beppu, and N. Gotoh, Homochiral asymmetric triacylglycerol isomers in egg yolk. J. Oleo Sci. 66, 1293-1299 (2017). [Paper (pdf)].

・ F. Beppu, K. Yasuda, A. Okada, Y. Hirosaki ,M. Okazaki, and N. Gotoh, Comparison on distribution of unsaturated fatty acid at sn-2 position of phospholipid and triacylglycerol between marine fishes and mammals. J. Oleo Sci. 66, 1217-1227 (2017). [Paper (pdf)].

・ D. Sato, K. Morino, F. Nakagawa, K. Murata, O. Sekine, F. Beppu, N. Gotoh, S. Ugi, and H. Maegawa, Acute effect of metformin on postprandial hypertriglyceridemia through delayed gastric emptying. Int. J. Mol. Sci. 18(6): 1282 (2017). [Paper (pdf)]

・ K. Nagao, K. Yoshinaga, T. Nagai, H. Mizobe, A. Yoshida, F. Beppu, and N. Gotoh, Comparison of the effect on apolipoprotein A1 and B secretion among trans fatty acid isomers using HepG2 cell. J. Oleo Sci. 66, 1175-1181 (2017). [Paper (pdf)].

・ F. Beppu, H. Li, K. Yoshinaga, T. Nagai, A. Yoshinda, A. Kubo, J. Kanda, and N. Gotoh, Dietary starfish oil prevents hepatic steatosis and hyperlipidemia in C57BL/6N mice fed high-fat diet. J. Oleo Sci. 66, 761-769 (2017). [Paper (pdf)]

・ K. Yoshinaga, J. Obi, T. Nagai, H. Iioka, A. Yoshida, F. Beppu, and N. Gotoh, Quantification of triacylglycerol molecular species in edible fats and oils by gas chromatography-flame ionization detector using correction factors. J. Oleo Sci. 66, 259-268 (2017). [Paper (pdf)]

・ S. Senarath, K. Yoshinaga, T. Nagai, A. Yoshida, F. Beppu, C. Jayasinghe, C. Devadawsond, and N. Gotoh, Quantitative analysis of distribution of cis-eicosenoic acid positional isomers in marine fish from the Indian Ocean. J. Oleo Sci. 66, 187-197 (2017). [Paper (pdf)]

・ F. Beppu, T. Kawamatsu, Y. Yamatani, T. Nagai, K. Yoshinaga, H. Mizobe, A. Yoshida, A. Kubo, J. Kanda, and N. Gotoh, Comparison of 13C-labeled fatty acid catabolic rates bound to the sn-1, sn-2, and sn-3 positions of triacylglycerol using 13C-labeled CO2 expired from mice. J. Oleo Sci. 66, 85-91 (2017).
[Paper (pdf)]


2016

N. Watanabe, T. Nagai, H. Mizobe, Kazuaki Yoshinaga, A. Yoshida, Y. Kitamura, T. Shimizu, F. Beppu, and N. Gotoh, Quantification of triacylglycerol positional isomers in rat milk. J. Oleo Sci. 65, 977-983 (2016). [Paper (pdf)]

・ C. Devadawson, C. Jayasinghe, R. Sivakanesan, S. Senarath, Fumiaki Beppu, and N. Gotoh, Comparative analysis of lipid content and fatty acid composition of commercially important fish and shellfish from Sri Lanka and Japan. J. Oleo Sci. 65, 543-556 (2016). [Paper (pdf)]

・後藤 直宏, <5> 脂肪酸の分類  Nutrition Care(ニュートリションケア)2016年1月号 .

・後藤直宏, <11> トランス脂肪酸  Nutrition Care(ニュートリションケア)2016年1月号.


2015

F. Beppu, M. Asanuma, Y. Kawamura, T. Nagai, K. Yoshinaga, H. Mizobe, K. Kojima, S. Kasatani, K. Nagao, A. Kubo, J. Kanda, and N. Gotoh, Trans-octadecenoic acid positional isomers have different accumulation and catabolism properties in mice. J. Oleo Sci., 64, 1159-1167(2015). [Paper (pdf)]

T. Nagai, N. Watanabe, K. Yoshinaga, H. Mizobe, K. Kojima, I Kuroda, Y. Odanaka, T. Saito, F. Beppu, and N. Gotoh, Abundances of triacylglycerol positional isomers and enantiomers comprised of a dipalmitoylglycerol backbone and short- and medium-chain fatty acids in bovine milk fat. J. Oleo Sci., 64, 943-952 (2015). [Paper (pdf)]

・ F. Beppu, K. Konno, T. Kawamatsu, T. Nagai, K. Yoshinaga, H. Mizobe, K. Kojima, H. Watanabe, and N. Gotoh, Comparison of catabolic rates of 13C-labeled palmitic acid bound to the alpha and beta positions of triacylglycerol using CO2 expired from mice. Eur. J. Lipid Sci. Technol. 117, 718-723 (2015). [Abstract]

・ R. Suo, H. Li, K. Yoshinaga, T. Nagai, H. Mizobe, K. Kojima, K. Nagao, F. Beppu, and N. Gotoh, Generation of tetracosahexaenoic acid in benthic marine organisms.
J. Oleo Sci. 64, 721-727 (2015). [Paper (pdf)]

・ K. Yoshinaga, Y. Kawamura, T. Kitayama, T. Nagai, H. Mizobe, K. Kojima, Y. Watanabe, S. Sato, F. Beppu, and N. Gotoh, Regiospecific distribution of trans-octadecenoic acid positional isomers in triacylglycerols of partially hydrogenated vegetable oil and ruminant fat. J. Oleo Sci. 64, 617-624 (2015). [Paper (pdf)]

・ K. Yoshinaga, K. Sasaki, H. Watanabe, K. Nagao, N. Inoue, B. Shirouchi, T. Yanagita, T. Nagai, H. Mizobe, K. Kojima, F. Beppu, and N. Gotoh, Differential effects of triacylglycerol positional isomers containing n-3 series highly unsaturated fatty acids on lipid metabolism in C57BL/6J mice. J. Nutr. Biochem. 26, 57-63 (2015). [Abstract]


・永井 利治, 後藤 直宏, 【総説】トリアシルグリセロール(TAG)異性体分析の発展と乳脂分析への応用, 乳業技術 64, 10-26 (2015).

・永井 利治, 後藤 直宏, 【総説】乳脂におけるトリアシルグリセロール(TAG)鏡像異性体分析の特徴, ミルクサイエンス 64, 139-149 (2015).

・後藤 直宏, 【基礎講座】脂質の化学的性質−脂質の劣化−, オレオサイエンス 15, 179-182 (2015).

・後藤 直宏, 【解説】脂質化学を理解するための共有結合入門, オレオサイエンス 15, 195-197 (2015).



2014

・ K. Nagao, K. Nakamitsu, H. Ishida, K. Yoshinaga, T. Nagai, H. Mizobe, K. Kojima, T. Yanagita, F. Beppu, and N. Gotoh, A comparison of the lipid-lowering effects of four different n-3 highly unsaturated fatty acids in HepG2 cell. J. Oleo Sci. 63, 979-985 (2014). [Paper (pdf)]

・ K. Yoshinaga, M. Asanuma, H. Mizobe, K. Kojima, T. Nagai, F. Beppu, and N. Gotoh, Characterization of cis- and trans-octadecenoic acid positional isomers in edible fat and oil using gas chromatography-flame ionization detector equipped with high polar ionic liquid capillary column. Food Chem. 160, 39-45 (2014). [Abstract]

・ K. Okusa, Y. Iwasaki, I. Kuroda, S. Miwa, M. Ohira, T. Nagai, H. Mizobe, N. Gotoh, T. Ikegami, D.V. MaCalley, and N. Tanaka, Effect of pressure on the selectivity of polymeric C18 and C30 stationary phases in reversed-phase liquid chromatography. Increase separation of isomeric fatty acid methyl esters, triacylglycerols, and tocopherols at high pressure. J. Chromatogr. A 1339, 86-95 (2014).[Abstract]

・ J. W. Lee, T. Nagai, N. Gotoh, E. Fukusaki, and T. Bamba, Profiling of regioisomeric triacylglycerols in edible oils by supercritical fluid chromatography/tandem mass spectrometry. J. Chromatogr. B 966, 193-199 (2014).. [Abstract]

・ 後藤 直宏, 【総説】脂質の構造に由来する保健機能と代謝能の評価手法, 脂質栄養学 23, 29-36 (2014). [Review (pdf)]

・ 後藤 直宏, 【総説】トランス脂肪酸問題と異性体 −工業型トランス脂肪酸と天然型トランス脂肪酸−, オレオサイエンス 14, 243-251 (2014).

・ 吉永 和明, 後藤 直宏, 【総説】トランス脂肪酸位置異性体分析技術の進展, ミルクサイエンス 63, 71-80 (2014). [Review (pdf)]

・ 後藤 直宏, 和田 俊, 角田 淳, タン ハイメン, 【特許】飼料原料用抗酸化組成物 特許第5429750.

・ 後藤 直宏, 和田 俊, 市岡 建司, 永井 利治, 【特許】抗酸化剤 特許第5610187.


2013

・ F. Kitamura, H. Watanabe, A. Umeno, Y. Yoshida, K. Kurata, and N. Gotoh, Oxidized trilinoleate and tridocosahexaenoate induce pica behavior and change locomotor activity. J. Oleo Sci. 62, 207-212 (2013). [Paper (pdf)]

・ K. Yoshinaga, T. Nagai, H. Mizobe, K. Kojima, and N. Gotoh, Simple method for the quantification of milk fat content in foods by LC-APCI-MS/MS using 1,2-dipalmitoyl-3-butyroyl-glycerol as an indicator. J. Oleo Sci. 62, 115-121 (2013). [Paper (pdf)]

・ K. Okada, E. Warabi, H. Sugimoto, M. Horie, N. Gotoh, K. Tokushige, E. Hashimoto, H. Utsunomiya, H. Takahashi, T. Ishii, M. Yamamoto, and J. Shoda, Deletion of Nrf2 leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet. J. Gastroenterol. 48, 620-632 (2013). [Abstract]

・ K. Yoshinaga, M. Asanuma, C. Xu, H. Mizobe, K. Kojima, T. Nagai, F. Beppu, and N. Gotoh, Resolution behavior of cis- and trans-octadecenoic acid isomers by AOCS official method using SP-2560 column. J. Oleo Sci. 62, 781-788 (2013). [Paper (pdf)]

・ N. Gotoh, T. Nagai, K. Yoshinaga, H. Mizobe, and H. Watanabe, Comparison of catabolic rates of fatty acids using stable isotope and isotope-ratio mass spectrometry. Lipid Tech. 25, 110-112 (2013)[Abstract].

・ C. Jayashinghe, N. Gotoh, and S. Wada, Pro-oxidant/antioxidant behaviour of ascorbic acid, tocopherol and plant extracts in n-3 highly unsaturated fatty acid oil-in-water emulsion. Food Chem.141, 3077-3084 (2013) [Abstract]

・ F. Beppu, T. Nagai, K. Yoshinaga, H. Mizobe, K. Kojima, and N. Gotoh, Quantification of triacylglycerol molecular species in cocoa butter using high-performance liquid chromatography equipped with nano quantity analyte detector. J. Oleo Sci. 62, 789-794 (2013). [Paper (pdf)]

・ T. Nagai, Y. Matsumoto, Y. Jiang, K. Ishikawa, T. Wakatabe, H. Mizobe, K. Yoshinaga, K. Kojima, I. Kuroda, T. Saito, F. Beppu, and N. Gotoh, Actual ratios of triacylglycerol positional isomers and enantiomers comprising saturated fatty acids and highly unsaturated fatty acids in fish and marine mammals. J. Oleo Sci. 62, 1009-1015 (2013). [Paper (pdf)]

・ 永井 利治, 後藤 直宏, 【総説】油脂の構造と機能 〜トリアシルグリセロール異性体分析の発展, オレオサイエンス 13, 355-363 (2013).

・ 永井 利治, 後藤 直宏, 【総説】HPLCによる食用油脂中のトリアシルグリセロール位置異性体・鏡像異性体分析, 和光純薬時報 81 (4), 10-12 (2013). [Review (pdf)]


2012


・ R. Shibata, N. Gotoh, A. Kubo, J. Kanda, T. Nagai, H. Mizobe, K. Yoshinaga, K. Kojima, H. Watanabe, and S. Wada, Comparison of catabolism rate of fatty acids to carbon dioxide in mice. Eur. J. Lipid Sci. Technol. 114, 1340-1344 (2012).[Abstract]

・ C. Jayashinghe, N. Gotoh, and S. Wada, Ragiospecific analysis of shark liver triacylglycerol: Docosahexaenoic acid primary bound in sn-2 position. J. Am. Oil Chem. Soc. 89,1873-1884 (2012).[Abstract]

・ N. Gotoh, Y. Matsumoto, T. Nagai, H. Mizobe, K. Yoshinaga, K. Kojima, I. Kuroda, Y. Kitamura, T. Shimizu, H. Ishida, and S. Wada, Actual ratio of triacylglycerol positional isomers in milk and cheese. J. Oleo Sci. 61, 173-180 (2012). [Paper (pdf)]



2011


・ N. Gotoh, S. Miyake, H. Takei, K. Sasaki, S. Okuda, M. Ishinaga, and S. Wada, Simple method for measuring the peroxide value in a colored lipid. Food Anal. Methods 4, 525-530 (2011). [Abstract]

・ N. Gotoh, Y. Matsumoto, T. Nagai, H. Mizobe, I. Otake, K. Ichioka, I. Kuroda, H. Watanabe, N. Noguchi, and S. Wada, Actual ratios of triacylglycerol positional isomers consisting of saturated and highly unsaturated fatty acids in fishes and marine mammals. Food Chem. 127, 467-472 (2011). [Abstract]

・ T. Nagai, H. Mizobe, I. Otake, K. Ichioka, K. Kojima, Y. Matsumoto, N. Gotoh, I. Kuroda, S. Wada, Enantiomeric separation of asymmetric triacylglycerol by recycle high-performance liquid chromatography with chiral column. J. Chromatogr. A 1218, 2880-2886 (2011). [Abstract]

・ N. Gotoh, D. Mashimo, T. Oka, K. Sekiguchi, M. Tange, H. Watanabe, N. Noguchi, and S. Wada, Analyses of marine-derived tocopherol in processed foods containing fish. Food Chem. 129, 279-283 (2011). [Abstract]

・ T. Nagai, N. Gotoh, H. Mizobe, K. Yoshinaga, K. Kojima, Y. Matsumoto, and S. Wada, Rapid separation of triacylglycerol positional isomers binding two saturated fatty acids using octacocyl silylation column. J. Oleo Sci. 60, 345-350 (2011). [Paper (pdf)]

・ N. Gotoh, S. Wada, and T. Nagai, Separation of asymmetric triacylglycerols into their enantiomers by recycle high-performance liquid chromatography. Lipid Tech. 23, 105-108 (2011). [Abstract]


2010

・ N. Gotoh, Y. Matsumoto, H. Yuji, T. Nagai, H. Mizobe, K. Ichioka, I. Kuroda, N. Noguchi, and S. Wada, Characterization of non-endcapped polymeric ODS column for the separation of triacylglycerol positional isomers. J. Oleo Sci. 59, 71-79 (2010). [Paper (pdf)]

・ N. Gotoh, Y. Noguchi, A. Ishihara, K. Yamaguchi, H. Mizobe, T. Nagai, I. Otake, K. Ichioka, and S. Wada, Highly unsaturated fatty acid might act as an antioxidant in emulsion system oxidized by azo compound. J. Oleo Sci. 59, 631-638 (2010). [Paper (pdf)]


2009

・ N. Gotoh, H. Watanabe, T. Oka, D. Mashimo, N. Noguchi, K. Hata, and S. Wada, Dietary marine-derived tocopherol has high biological availability in mice relative to alpha-tocopherol. Lipids 44, 133-143 (2009). [Abstract]

・ K. Sato, T. Kigawa, S. Ueno, N. Gotoh, S. Wada, Polymorphic behavior of structured fats including stearic acid and ω-3 polyunsaturated fatty acids. J. Am Oil Chem. Soc. 86, 297-300 (2009). [-> Look inside]

・ N. Gotoh, K. Nagao, S. Onoda, B. Shirouchi, K. Furuya, T. Nagai, H. Mizobe, K. Ichioka, H. Watanabe, T. Yanagita, and S. Wada, Effects of three different highly purified n-3 series highly unsaturated fatty acids on lipid metabolism in C57BL/KsJ-db/db mice. J. Agri. Food Chem. 57, 11047-11054 (2009). [Abstract]